Grant

PTH compounds with low peak-to-trough ratios

Patent Number US-11857603-B2

Publication Year 2024

Granted Year: 2024

Application Year 2022

Priority Year 2016

Jurisdiction US

Status Active

Inventors

SPROGØE KENNETT HOLTEN ANDERSEN LARS KARPF DAVID BRIAN CLEEMANN FELIX MAITRO GUILLAUME KRUSCH MATHIAS WEGGE THOMAS ZETTLER JOACHIM

Applicants

  1. Ascendis Pharma Bone Diseases AS
  2. [NORA names: Ascendis Pharma; Private Research]

Abstract

The present invention relates to a pharmaceutical composition comprising a PTH compound, wherein after subcutaneous administration the pharmacokinetic profile of the PTH compound exhibits a peak to trough ratio of less than 4 within one injection interval.

Patent Family Records (36)

PTH Compounds with Low Peak-To-Trough Ratios  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2024, US-20240173385-A1

PTH compounds with low peak-to-trough ratios

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2024, US-11857603-B2

PTH compounds with low peak-to-trough ratios  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2024, AU-2017336251-B2

PTH Compounds with Low Peak-To-Trough Ratios  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, US-20230218722-A1

PTH compounds with low peak-to-trough ratios  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, US-11759504-B2

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGOE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, SI-3518961-T1

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, RS-64177-B1

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, PL-3518961-T3

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, LT-3518961-T

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES A SPROGE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, KR-20230170810-A

PTH compounds with low peak-to-trough ratios  

아센디스 파마 본 디지즈 에이/에스 КАРПФ, Дэвид Брайан, СПРОГЕЕ, Кеннетт, ХОЛЬТЕН-АНДЕРСЕН, Ларс, (...more)

2023, KR-102611820-B1

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGOE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, HU-E062009-T2

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, HR-P20230383-T1

PTH compounds with low peak-to-valley ratios  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, ES-2943720-T3

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, EP-4218795-A3

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, EP-4218795-A2

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, EP-3518961-B1

PTH compounds with low peak to trough ratios  

ASCENDIS PHARMA BONE DISEASES AS HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, KARPF DAVID BRIAN, (...more)

2023, DK-3518961-T3

PTH compounds with low peak-to-valley ratio  

Ascendis Pharma Bone Diseases AS SPROGOE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2023, CN-117257922-A

PTH compounds with low peak-to-valley ratio  

Ascendis Pharma Bone Diseases AS SPROGOEE KENNETT, L. Holden-Anderson, D.B. Kapf

2023, CN-109789188-B

PTH COMPOUNDS WITH LOW PEAK-TO-MINIMUM RATIOS  

Astsendis Farma Boun Dizizis A/S SPROGEE Kennett, KHOLTEN-ANDERSEN LARS, KARPF DEVID BRAJAN

2022, RU-2766959-C2

PTH compounds with low peak-to-trough ratios  

Ascendis Pharma Bone Diseases AS KENNETT SPROGOE, LARS HOLTEN-ANDERSEN, DAVID BRIAN KARPF

2022, JP-2022116302-A

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2020, US-20200360488-A1

PTG CONNECTIONS WITH LOW PEAK TO MINIMUM RATIO  

Асцендис Фарма Боун Дизизис А/С КАРПФ, Дэвид Брайан, СПРОГЕЕ, Кеннетт, ХОЛЬТЕН-АНДЕРСЕН, Ларс, (...more)

2020, RU-2019112919-A

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2019, ZA-201901813-B

PTH Compounds with Low Peak-To-Trough Ratios  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2019, US-20190282668-A1

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2019, SG-11201901558V-A

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS.  

ASCENDIS PHARMA BONE DISEASES AS KENNETT SPROGØE, LARS HOLTEN-ANDERSEN, DAVID BRIAN KARPF

2019, MX-2019003182-A

PTH COMPOUNDS WITH LOW RELATIONSHIP BETWEEN PEAK AND MINIMUM LEVEL  

ASCENDIS PHARMA BONE DISEASES AS HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, KARPF DAVID BRIAN, (...more)

2019, MA-46345-A

PTH compound with low peak to trough ratio  

ASCENDIS PHARMA BONE DISEASES A SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2019, KR-20190062497-A

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2019, EP-3518961-A1

PTH compound with low peak-to-valley ratio  

Arsendis Drug Bone Disease Co Ltd SPROGOE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2019, CN-109789188-A

pth compounds with low peak-to-valley ratios  

ASCENDIS PHARMA BONE DISEASES AS DAVID BRIAN KARPF, KENNETT SPROGØE, LARS HOLTEN-ANDERSEN

2019, BR-112019005793-A2

PTH compounds with low peak-to-trough ratios  

Ascendis Pharma Bone Diseases AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2019, AU-2017336251-A1

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

ASCENDIS PHARMA BONE DISEASES AS SPROGØE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2018, WO-2018060312-A1

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS  

Ascendis Pharma Bone Diseases AS SPROGOE KENNETT, HOLTEN ANDERSEN LARS, HOLTEN-ANDERSEN LARS, (...more)

2018, CA-3037447-A1

Data Provider: Digital Science