N/A

PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS

Patent Number SG-11201901558V-A

Publication Year 2019

Application Year 2017

Priority Year 2016

Jurisdiction SG

Status N/A

Inventors

SPROGØE KENNETT HOLTEN ANDERSEN LARS KARPF DAVID BRIAN

Applicants

  1. ASCENDIS PHARMA BONE DISEASES AS
  2. [NORA names: Ascendis Pharma; Private Research]

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 05 April 2018 (05.04.2018) WIP0 I PCT ~~~~~~~~~~~~~ 01110101onDV10 0III11010100111Dlmoino oimIE (10) International Publication Number WO 2018/060312 Al (51) International Patent Classification: A61K 38/29 (2006.01) A61K 47/34 (2017.01) A61K 9/00 (2006.01) (21) International Application Number: PCT/EP2017/074594 (22) International Filing Date: 28 September 2017 (28.09.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 16191454.4 29 September 2016 (29.09.2016) EP 17155846.3 13 February 2017 (13.02.2017) EP (71) Applicant: ASCENDIS PHARMA BONE DISEASES A/ S [DK/DK]; Tuborg Boulevard 5, 2900 Hellerup (DK). (72) Inventors: SPROGOE, Kennett; Vengestien 7, 2840 Holte (DK). HOLTEN-ANDERSEN, Lars; Rodtjornevej 8, st., 2720 Vanlose (DK). KARPF, David Brian; 203 Sherland Ave., Mountain View, California 94043 (US). (74) Agent: BUCHEL, Edwin; Isenbruck Bosl Horschler LLP Patentanwalte, EASTSITE ONE, Seckenheimer LandstraBe 4, 68163 Mannheim (DE). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) (54) Title: PTH COMPOUNDS WITH LOW PEAK-TO-TROUGH RATIOS 0 (57) : The present invention relates to a pharmaceutical composition comprising a PTH compound, wherein after subcutaneous \" administration the pharmacokinetic profile of the PTH compound exhibits a peak to trough ratio of less than 4 within one injection 0 interval.

Patent Family Records (36)

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