Article, 2024
P-205 THE SAFECHROM PROJECT - EVIDENCE FROM A CROSS-SECTIONAL STUDY SHOWS THAT HEXAVALENT CHROMIUM IS STILL A CONCERN IN SWEDEN
Occupational Medicine,
ISSN
0962-7480,
1471-8405,
Volume 74,
Supplement_1,
Page 0,
10.1093/occmed/kqae023.0747
Contributors
Jiang, Zheshun
0000-0001-7263-166X
[1]
Schenk, Linda
0000-0003-3799-4814
[2]
Assarsson, Eva
[1]
Albin, Maria
0000-0002-6613-4437
[2]
Bertilsson, Helen
[3]
Dock, Eva
[1]
Hagberg, Jessika
[4]
Karlsson, Lovisa E
[5]
Kines, Pete
0000-0002-8660-6366
[6]
Krais, Anette M
[1]
Ljunggren, Stefan A
0000-0003-3984-3964
[7]
Lundh, Thomas
0000-0002-2780-3263
[1]
Modig, Lars
[3]
Möller, Rickie
[8]
Pineda, Daniela
0000-0002-6639-1652
[1]
Ricklund, Niklas
[5]
Saber, Anne Thoustrup
[6]
Storsjö, Tobias
[8]
Amir, Evana Taher
[2]
Tinnerberg, Håkan
[8]
[9]
Tondel, Martin Olof
0000-0003-4469-2451
[10]
[11]
Vogel, Ulla Birgitte
0000-0001-6807-1524
[6]
Wiebert, Pernilla
0000-0002-6367-0701
[2]
Engfeldt, Malin
0000-0001-8855-0936
[1]
Broberg, Karin E
0000-0002-5862-468X
[2]
Affiliations
- [1]
Lund University
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [2]
Karolinska Institutet
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [3]
Umeå University
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [4]
Örebro University
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [5]
Örebro University Hospital
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
(... more)
- [6]
National Research Centre for the Working Environment
[NORA names:
NFA National Research Centre for the Working Environment;
Governmental Institutions; Denmark; Europe, EU; Nordic; OECD];
- [7]
Linköping University
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [8]
Sahlgrenska University Hospital
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [9]
University of Gothenburg
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [10]
Uppsala University
[NORA names:
Sweden; Europe, EU; Nordic; OECD];
- [11]
Uppsala University Hospital
[NORA names:
Sweden; Europe, EU; Nordic; OECD]
(less)
Abstract
Abstract Introduction Hexavalent chromium Cr(VI) is a human carcinogen, but the current exposure to Cr(VI) at Swedish workplaces is unknown. Methods Recruitment of 113 workers with potential Cr(VI) exposure and 72 controls was combined with measurements of inhalable Cr(VI) (only exposed workers) and total Cr in urine and red blood cells (RBC), Bayesian analysis of occupational exposure limit (OEL) compliance was used, as well as the Swedish job-exposure-matrix. Results Exposed workers performed processing of metal products, steel production, welding, and plating. The geometric mean concentration of inhalable Cr(VI) in exposed workers was 0.15 μg/m3. Eight workers (7%) exceeded the Swedish OEL (5 μg/m3), and the share of OEL exceedances was estimated to be up to 19.6% for stainless steel welders. Urine- and RBC-Cr were significantly higher in exposed workers compared with controls. Workers with inferred non-acceptable local exhaustion ventilation showed significantly higher inhalable Cr(VI), urine- and RBC-Cr than those with acceptable ventilation. Workers with inferred correct use of respiratory protection had higher inhalable Cr(VI), and, paradoxically, higher urine- and RBC-Cr concentrations than workers with incorrect use. We estimate that ~17 900 Swedish workers are occupationally exposed to Cr(VI) today. Discussion Our study showed that although most air measurements were relatively low, 7% exceeded the OEL, and particularly stainless steel workers are at risk for exceeding the OEL. The existing protective measures implemented at workplaces are still inadequate and insufficient. Conclusion Some workers in Sweden are exposed to high levels of the non-threshold carcinogen Cr(VI). National strategies aligned with European strategies are needed to eliminate occupational cancer.
Keywords
Bayesian analysis,
Cr,
Cr(VI,
European strategy,
Sweden,
Swedish occupational exposure limit,
Swedish workers,
Swedish workplaces,
acceptable ventilation,
air,
air measurements,
blood cells,
cancer,
carcinogenic Cr(VI,
carcinogens,
cells,
chromium Cr(VI,
compliance,
concentration,
control,
evidence,
exceedance,
exhaust ventilation,
exposed workers,
exposure,
exposure limits,
geometric mean concentrations,
hexavalent,
hexavalent chromium Cr(VI,
human carcinogen,
inhaled Cr(VI,
job-exposure-matrix,
levels,
limitations,
local exhaust ventilation,
measurements,
metal products,
national strategy,
occupational cancer,
occupational exposure limits,
plate,
process,
process of metal production,
production,
project evidence,
protection,
protection measures,
recruitment,
red blood cells,
respiratory protection,
results,
risk,
show,
stainless steel welders,
steel,
steel production,
steel workers,
strategies,
study,
study show,
urine,
ventilation,
welders,
welding,
workers,
workplace
Data Provider: Digital Science