Article, 2024

Surface effects of polyelectrolyte multilayer films on bioactive glass scaffolds

Materials Letters, ISSN 1873-4979, 0167-577X, Volume 370, Page 136857, 10.1016/j.matlet.2024.136857

Contributors

Imbir, Gabriela 0000-0001-9117-0184 (Corresponding author) [1] [2] Baino, Francesco 0000-0001-8860-0497 [3] Miola, Marta 0000-0002-1440-6146 [3] Mzyk, Aldona 0000-0002-4998-5491 [4] Marzec, Mateusz Marek 0000-0001-5025-4816 [5] Verné, Enrica 0000-0002-8649-4739 [3]

Affiliations

  1. [1] Institute of Metallurgy and Materials Science
    2. [NORA names: Poland; Europe, EU; OECD];
  2. [2] Institute of Nuclear Physics, Polish Academy of Sciences
    3. [NORA names: Poland; Europe, EU; OECD];
  3. [3] Polytechnic University of Turin
    4. [NORA names: Italy; Europe, EU; OECD];
  4. [4] Technical University of Denmark
    5. [NORA names: DTU Technical University of Denmark; University; Denmark; Europe, EU; Nordic; OECD];
  5. [5] AGH University of Krakow
    6. [NORA names: Poland; Europe, EU; OECD]

Abstract

Bioactive glasses are crucial in regenerative medicine, meeting the demand for biomaterial–bone tissue integration. This study explores the effect of polymer-based films on bioactive glass, evaluating their impact on biological and physicochemical properties to potentially improve cell-material interaction. Polysaccharide-based films were used to modify a silica-based bioactive glass, analyzing surface features, composition, and bioactivity upon immersion in simulated body fluid. Surface characteristics investigation confirmed successful functionalization, but no notable differences were found in bioactivity between unmodified and polymer-coated materials. Therefore, the polymer-based coating is not detrimental for the scaffold’s apatite-forming ability, and is expected to facilitate bone cell attachment, which deserves future investigation.

Keywords

ability, apatite-forming ability, attachment, bioactive glass, bioactive glass scaffolds, bioactivity, body fluids, bone, bone cell attachment, cell attachment, cell-material interactions, characteristics investigation, coating, composition, effect, features, films, fluid, function, glass, glass scaffolds, immersion, impact, integration, interaction, investigation, materials, medicine, multilayer films, physicochemical properties, polyelectrolyte multilayer films, polymer-based coatings, polymer-based films, polymer-coated materials, polysaccharide-based films, properties, regenerative medicine, scaffolds, silica-based bioactive glasses, simulated body fluid, study, surface, surface effects, surface features, tissue integrity

Funders

  • National Science Center

Data Provider: Digital Science

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