Article,
Clinical Evaluation of a New Spectral-Domain Optical Coherence Tomography-Based Biometer
Contributors
Alió, Jorge Luciano
0000-0003-2666-3366
[1]
[2]
Martínez-Abad, Antonio
0000-0002-6656-2917
[2]
Murta, Joaquim Neto
0000-0001-8926-5176
[5]
Cantó-Cerdán, Mario
0000-0001-8887-4308
[2]
Piñero, David Pablo
0000-0002-1546-4807
[6]
Affiliations
- [1] Miguel Hernandez University [NORA names: Spain; Europe, EU; OECD];
- [2] Research and Development Department, Vissum Grupo Miranza, 03016 Alicante, Spain;, jlalio@vissum.com, (J.L.A.);, marina.jose@vissum.com, (M.J.-M.);, anmartinez@vissum.com, (A.M.-A.);, abplaza@vissum.com, (A.B.P.-P.);, mcanto@vissum.com, (M.C.-C.) [NORA names: Spain; Europe, EU; OECD];
- [3] CSO (Construzioni Strumenti Oftalmici), 50018 Scandicci, Italy;, f.versaci@csoitalia.it [NORA names: Italy; Europe, EU; OECD];
- [4] Aarhus University Hospital [NORA names: Central Denmark Region; Hospital; Denmark; Europe, EU; Nordic; OECD];
- [5] University of Coimbra [NORA names: Portugal; Europe, EU; OECD];
(... more)
Abstract
The VEMoS-AXL system is a new optical biometer based on spectral domain optical coherence tomography (SD-OCT) that has been tested in terms of intrasession repeatability and compared with a swept-source optical coherence tomography biometer (SS-OCT), which is recognized as the gold standard for the performance of an agreement analysis. A biometric analysis was performed three consecutive times in 120 healthy eyes of 120 patients aged between 18 and 40 years with the SD-OCT system, and afterwards, a single measurement was obtained with the SS-OCT system. Within-subject standard deviations were 0.004 mm, 4.394 µm, and 0.017 mm for axial length (AL), central corneal thickness (CCT), and anterior chamber depth (ACD) measures obtained with the SD-OCT biometer, respectively. The agreement between devices was good for AL (limits of agreement, LoA: -0.04 to 0.03 mm) and CCT (LoA: -4.36 to 14.38 µm), whereas differences between devices were clinically relevant for ACD (LoA: 0.03 to 0.21 mm). In conclusion, the VEMoS-AXL system provides consistent measures of anatomical parameters, being most of them interchangeable with those provided by the SS-OCT-based gold standard.
