open access publication

Article, 2024

Validation of Obstetric Diagnosis and Procedure Codes in the Danish National Patient Registry in 2017

Clinical Epidemiology, ISSN 1179-1349, Volume 16, Pages 121-130, 10.2147/clep.s441123

Contributors

Herskind, Kamille [1] Jensen, Peter Bjødstrup 0000-0001-5435-9092 [1] Vinter, Christina Anne 0000-0001-5084-6053 [1] [2] Krebs, Lone 0000-0001-5433-4776 [3] [4] Eskildsen, Lene Friis [4] Broe, Anne 0000-0002-4149-8808 [1] [5] Pottegård, Anton 0000-0001-9314-5679 [1] Bliddal, Mette 0000-0002-7637-3730 (Corresponding author) [1]

Affiliations

  1. [1] University of Southern Denmark
  2. [NORA names: SDU University of Southern Denmark; University; Denmark; Europe, EU; Nordic; OECD];
  3. [2] Odense University Hospital
  4. [NORA names: Region of Southern Denmark; Hospital; Denmark; Europe, EU; Nordic; OECD];
  5. [3] University of Copenhagen
  6. [NORA names: KU University of Copenhagen; University; Denmark; Europe, EU; Nordic; OECD];
  7. [4] Amager and Hvidovre Hospital
  8. [NORA names: Capital Region of Denmark; Hospital; Denmark; Europe, EU; Nordic; OECD];
  9. [5] IQVIA (United Kingdom)
  10. [NORA names: United Kingdom; Europe, Non-EU; OECD]

Abstract

Purpose: This study aimed to systematically evaluate the validity of variables related to pregnancy, delivery, and key characteristics of the infant in the Danish National Patient Register using maternal medical records as the reference standard. Patients and Methods: We reviewed medical records of 1264 women giving birth in the Region of Southern Denmark during 2017. We calculated positive (PPV) and negative (NPV) predictive values, sensitivity, and specificity to estimate the validity of 49 selected variables. Results: The PPV was ≥0.90 on most pregnancy-related variables including parity, pre-gestational BMI, diabetes disorders, and previous cesarean section, while it was lower for hypertensive disorders, especially mild to moderate preeclampsia (0.49, 95% CI 0.32-0.66). Sensitivity ranged from 0.80 to 1.00 on all pregnancy-related variables, except hypertensive disorders (sensitivity 0.38-0.71, lowest for severe preeclampsia). On most delivery-related variables including obstetric surgical procedures (eg cesarean section and induction of labor), pharmacological pain-relief, and gestational age at delivery, PPV's ranged from 0.98 to 1.00 and the corresponding sensitivities from 0.87 to 1.00. Regarding infant-related variables, both the APGAR score registered five minutes after delivery and birthweight yielded a PPV of 1.00. Conclusion: Obstetric coding in the Danish National Patient Register shows very high validity and completeness making it a valuable source for epidemiologic research.

Keywords

Apgar, Apgar score, BMI, Danish, Danish National Patient Register, Danish National Patient Registry, Denmark, NPV, National Patient Register, National Patient Registry, PPV, Patient Register, Patient Registry, Region of Southern Denmark, Southern Denmark, age, birth, birthweight, cesarean, cesarean section, characteristics, code, completion, delivery, delivery-related variables, diabetes, diabetic disorders, diagnosis, disorders, epidemiological research, gestational age, hypertensive disorders, infants, maternal medical records, medical records, mild to moderate preeclampsia, minutes, moderate preeclampsia, obstetric codes, obstetric diagnosis, obstetric surgical procedure, pain relief, parity, patients, pharmacological pain relief, pre-gestational BMI, predictive value, preeclampsia, pregnancy, pregnancy-related variables, procedure, procedure codes, records, reference, reference standard, region, register, registry, research, reviewed medical records, scores, section, sensitivity, source, specificity, standards, study, surgical procedures, validity, values, variables, variables related to pregnancy, women

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