open access publication

Article, 2024

Identifying Ontarians with Type 2 Diabetes Mellitus in Administrative Data: A Comparison of Two Case Definitions

Diabetes Therapy, ISSN 1869-6953, 1869-6961, Volume 15, 3, Pages 677-689, 10.1007/s13300-024-01535-4

Contributors

Houlden, Robyn Leslie (Corresponding author) [1] Thayalan, Nilasha [1] Shi, Scott [2] Kukaswadia, Atif A 0000-0002-9419-2415 [2] Mau, Godfrey 0009-0006-8982-7558 [3] Liu, Aiden R [4]

Affiliations

  1. [1] Queen's University
  2. [NORA names: Canada; America, North; OECD];
  3. [2] IQVIA Solutions Canada Inc, Mississauga, ON, Canada
  4. [NORA names: Canada; America, North; OECD];
  5. [3] Novo Nordisk (Canada)
  6. [NORA names: Canada; America, North; OECD];
  7. [4] Novo Nordisk (Denmark)
  8. [NORA names: Novo Nordisk; Private Research; Denmark; Europe, EU; Nordic; OECD]

Abstract

IntroductionThis study compared two previously validated sensitive and specific diabetes case definitions to explore the impact of different classification methods in Ontario ICES administrative data.MethodsThis study included patients captured by the Ontario Diabetes Database with type 2 diabetes using either the sensitive cohort definition (≥ 2 physician visits for diabetes within 1 year or ≥ 1 drug claim for diabetes or ≥ 1 hospitalization with diabetes), or the specific cohort definition (≥ 3 physician visits for diabetes within 1 year), between October 1, 2013 to September 30, 2015. Each cohort's demographic and clinical features were described using descriptive analysis.ResultsUsing sensitive and specific definitions, 1,093,812 and 783,228 patients with type 2 diabetes were identified, respectively. Overall, the demographic and clinical characteristics were similar between cohorts. Patients in the sensitive cohort had mean age of 64.1 years and were 52.4% male, compared to 64.8 years and 53.6% male in the specific cohort. In the sensitive and specific cohorts respectively, 64.4% and 55.7% of patients reported one-year mean HbA1c of < 7% (53 mmol/mol) and 25.3% and 31.5% reported levels between 7.0–8.5% (53–69 mmol/mol).ConclusionsAlthough sample sizes were different between sensitive and specific cohorts, demographic and clinical characteristics were similar.

Keywords

Administrative Data, Diabetes Database, HbA1c, IntroductionThis, IntroductionThis study, MethodsThis, MethodsThis study, Ontarians, Ontario, Ontario Diabetes Database, administration, administrative data, age, case definition, cases, characteristics, classification, classification method, clinical characteristics, clinical features, cohort, cohort definitions, comparison, data, database, definition, features, impact, levels, male, mean HbA1c, mellitus, method, patients, sample size, sensitive cohort, size, specific definitions, study, type, type 2 diabetes, type 2 diabetes mellitus, years

Funders

  • Novo Nordisk (Denmark)

Data Provider: Digital Science