Article,
The effect of inosine on the spectroscopic properties and crystal structure of a NIR-emitting DNA-stabilized silver nanocluster
Contributors
Cerretani, Cecilia
0000-0002-3048-5438
[1]
Liisberg, Mikkel Baldtzer
0000-0001-7623-5453
[1]
Rück, Vanessa
0000-0002-7403-3118
[1]
Kondo, Jiro
0000-0002-5682-3685
(Corresponding author)
[2]
Vosch, Tom André Jos
0000-0001-5435-2181
(Corresponding author)
[1]
Affiliations
- [1] University of Copenhagen [NORA names: KU University of Copenhagen; University; Denmark; Europe, EU; Nordic; OECD];
- [2] Sophia University [NORA names: Japan; Asia, East; OECD]
Abstract
The effect of replacing guanosines with inosines in the two stabilizing strands (5'-CACCTAGCGA-3') of the NIR emissive DNA-Ag16NC was investigated. The spectroscopic behavior of the inosine mutants is position-dependent: when the guanosine in position 7 was exchanged, the nanosecond fluorescence decay time shortened, while having the inosine in position 9 made the decay time longer. Thanks to structural information gained from single crystal X-ray diffraction measurements, it was possible to propose a mechanistic origin for the observed changes.
Keywords
DNA-stabilized silver nanoclusters,
NIR,
X-ray diffraction measurements,
behavior,
changes,
crystal,
crystal X-ray diffraction measurements,
crystal structure,
decay,
decay time,
diffraction measurements,
effect,
effects of inosine,
fluorescence decay time,
guanosine,
information,
inosine,
measurements,
mechanistic origin,
mutants,
nanoclusters,
origin,
position,
position 7,
position 9,
properties,
silver nanoclusters,
spectroscopic behavior,
spectroscopic properties,
strands,
structural information,
structure,
time
