Article, 2015

Carotid stent-assisted thrombectomy in acute ischemic stroke

Future Cardiology, ISSN 1744-8298, 1479-6678, Volume 11, 5, Pages 615-632, 10.2217/fca.15.54

Contributors

Steglich-Arnholm, Henrik 0000-0002-9621-4251 [1] Krieger, Derk Wolfgang (Corresponding author) [1] [2]

Affiliations

  1. [1] Rigshospitalet
  2. [NORA names: Capital Region of Denmark; Hospital; Denmark; Europe, EU; Nordic; OECD];
  3. [2] University of Copenhagen
  4. [NORA names: KU University of Copenhagen; University; Denmark; Europe, EU; Nordic; OECD]

Abstract

Acute carotid occlusion or near-occlusion with concomitant intracranial embolism cause severe acute ischemic strokes in patients. These concomitant occlusions have suggested poor response to intravenous thrombolysis and complicate endovascular treatment. Nevertheless, endovascular stent-assisted thrombectomy may improve outcome in patients but the treatment is not without concerns. Required antiplatelet therapy to prevent stent thrombosis may increase the rate of intracranial hemorrhage, especially after recent thrombolysis. Furthermore, technical difficulties in access of the intracranial vasculature may cause adverse events, even in the hands of experienced interventionalists. These concerns currently defy the treatment in being recommended for general use and only on a compassionate basis. However, recent patient series have suggested reasonable safety and efficacy for carotid stent-assisted thrombectomy.

Keywords

acute carotid occlusion, acute ischemic stroke, adverse events, antiplatelet therapy, basis, carotid, carotid occlusion, compassionate basis, concerns, concomitant occlusion, difficulties, efficacy, embolization, endovascular treatment, events, hand, hemorrhage, interventionalists, intracranial embolism, intracranial hemorrhage, intracranial vasculature, intravenous thrombolysis, ischemic stroke, near-occlusion, occlusion, outcomes, patient series, patients, rate, rate of intracranial hemorrhage, response to intravenous thrombolysis, safety, series, severe acute ischemic stroke, stent, stent thrombosis, stent-assisted thrombectomy, stroke, technical difficulties, therapy, thrombectomy, thrombolysis, thrombosis, treatment, vasculature

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