Application

HIGHLY POTENT ISVD COMPOUNDS CAPABLE OF SUBSTITUTING FOR FVIII(A)

Patent Number US-20240067944-A1

Publication Year 2024

Application Year 2023

Priority Year 2022

Jurisdiction US

Status Pending

Inventors

VEGGE ANDREAS STEFFENSEN SOREN BUYSE MARIE ANGE HUBALEK FRANTISEK FULLE SIMONE NORRMAN MATHIAS GRANATA DANIELE JOHANSSON EVA BJELKE JAIS ROSE LUND JACOB SASSENE PHILIP JONAS GREISEN PER J EGEBJERG THOMAS DE TAVERNIER EVELYN

Applicants

  1. Novo Nordisk (Denmark)
  2. [NORA names: Novo Nordisk; Private Research; Denmark; Europe, EU; Nordic; OECD]

Abstract

The present invention provides ISVD polypeptide derivatives capable of binding coagulation Factor IX(a) and Factor X(a) which are highly potent and provide a sufficiently long half-life such to allow for effective subcutaneous—as well as peroral administration. The ISVD polypeptides derivatives disclosed herein are thus suitable for treatment of haemophilia A, haemophilia A with inhibitors and acquired haemophilia A by various routes of administration including subcutaneous and peroral administration.

Patent Family Records (6)

HIGHLY POTENT ISVD COMPOUNDS CAPABLE OF SUBSTITUTING FOR FVIII(A)

Novo Nordisk (Denmark), Novo Nordisk AS VEGGE ANDREAS, STEFFENSEN SOREN, BUYSE MARIE ANGE, (...more)

2024, US-20240067944-A1

HIGHLY POTENT ISVD COMPOUNDS CAPABLE OF SUBSTITUTING FOR FVIII(A)  

NOVO NORDISK AS, Novo Nordisk (Denmark) VEGGE ANDREAS, FULLE SIMONE, NORRMAN MATHIAS, (...more)

2024, TW-202409091-A

Highly potent ISVD compounds capable of substituting for FVIII(a)  

NOVO NORDISK A, Novo Nordisk (Denmark) VEGGE ANDREAS, FULLE SIMONE, NORRMAN MATHIAS, (...more)

2024, KR-20240007881-A

Highly potent ISVD compounds that can replace FVIII(a)  

Novo Nordisk (Denmark), Novo Nordisk AS アンドレアス・ヴェッゲ, エヴァ・ヨハンソン, エヴリン・デ・タヴェルニエ, (...more)

2024, JP-7459354-B2

Highly potent ISVD compounds that can replace FVIII(a)  

Novo Nordisk (Denmark), Novo Nordisk AS アンドレアス・ヴェッゲ, エヴァ・ヨハンソン, エヴリン・デ・タヴェルニエ, (...more)

2024, JP-2024073606-A

Highly Potent ISVD Compounds that Can Replace FVIII(a)  

Novo Nordisk (Denmark), Novo Nordisk AS ANDREAS VEGGE, SIMONE FULLE, MATHIAS NORRMAN, (...more)

2024, JP-2024020151-A

Data Provider: Digital Science