Grant

Separation of 2'-O-fucosyllactose from fermentation broth

Patent Number DE-202015009782-U1

Publication Year 2020

Granted Year: 2020

Application Year 2015

Priority Year 2014

Jurisdiction DE

Status Active

Applicants

  1. Glycom AS
  2. [NORA names: Glycom; Private Research]

Abstract

Crystallized 2-O'-fucusyllactose (2'-FL) produced by a process comprising the following steps:
i. Culturing a genetically modified cell with a recombinant gene coding for a 1,2-fucosyltransferase and capable of producing 2'-FL by fucosylation of lactose in an aqueous culture medium containing lactose,
ii. Separating the aqueous solution of non-carbohydrate particles and contaminants of the aqueous culture medium, the aqueous solution comprising 2'-FL and a fucosylated carbohydrate other than 2'-FL, the aqueous solution being 35-80% by weight with respect to their carbohydrate content , 45-95% by weight of the carbohydrates in the aqueous solution being 2'-FL, and
iii. Crystallize 2'-FL from the aqueous solution.

Patent Family Records (12)

Separation of 2-O-fucosyl-lactose from fermentation broth  

Glycom AS MATWIEJUK MARTIN, CHASSAGNE PIERRE, OSZTROVSZKY GYÖRGYI, (...more)

2024, ES-2968677-T3

SEPARATION OF 2'-O-FUCOSYLLACTOSE FROM FERMENTATION BROTH  

Glycom AS MATWIEJUK MARTIN, CHASSAGNE PIERRE, OSZTROVSZKY GYÖRGYI, (...more)

2023, EP-3154995-B1

SEPARATION OF 2'-O-FUCOSYLLACTOSE FROM FERMENTATION BROTH  

GLYCOM AS MATWIEJUK MARTIN, CHASSAGNE PIERRE, DEKANY GYULA, (...more)

2023, DK-3154995-T3

Separation of 2'-FL from a fermentation culture solution  

GLYCOM AS GYULA DÉKANY, MARKUS HEDEROS, GYÖRGYI OSZTROVSZKY, (...more)

2023, DK-202000086-Y4

Separation of 2′-FL from a fermentation broth  

GLYCOM AS MARKUS HEDEROS, GYÖRGYI OSZTROVSZKY, MARTIN MATWIEJUK, (...more)

2022, DK-202100114-Y4

SEPARATION OF 2'-FL FROM A FERMENTATION BROTH  

GLYCOM AS MARKUS HEDEROS, GYÖRGYI OSZTROVSZKY, MARTIN MATWIEJUK, (...more)

2021, DK-202100114-U1

SEPARATION OF 2'-FL FROM A FERMENTATION BROTH  

GLYCOM AS GYULA DÉKANY, MARKUS HEDEROS, GYÖRGYI OSZTROVSZKY, (...more)

2020, DK-202000086-U1

SEPARATION OF 2'-O-FUCOSYLLACTOSE FROM FERMENTATION BROTH  

GLYCOM AS GYULA DÉKANY, MARKUS HEDEROS, GYÖRGYI OSZTROVSZKY, (...more)

2020, DK-201900111-U1

Separation of 2'-O-fucosyllactose from fermentation broth

Glycom AS

2020, DE-202015009782-U1

SEPARATION OF 2'-O-FUCOSYLLACTOSE FROM FERMENTATION BROTH  

Glycom AS MATWIEJUK MARTIN, CHASSAGNE PIERRE, OSZTROVSZKY GYÖRGYI, (...more)

2017, EP-3154995-A4

SEPARATION OF 2'-O-FUCOSYLLACTOSE FROM FERMENTATION BROTH  

Glycom AS MATWIEJUK MARTIN, CHASSAGNE PIERRE, OSZTROVSZKY GYÖRGYI, (...more)

2017, EP-3154995-A1

SEPARATION OF 2'-O-FUCOSYLLACTOSE FROM FERMENTATION BROTH  

GLYCOM AS MATWIEJUK MARTIN, CHASSAGNE PIERRE, OSZTROVSZKY GYÖRGYI, (...more)

2015, WO-2015188834-A1

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