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PRODUCTION OF SATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACID ACYL ACETATES IN Yeast
Inventors
Borodina, Irina
0000-0002-8452-1393
Holkenbrink, Carina
Dam, Marie Inger
0000-0001-7833-0606
Löfstedt, Christer
0000-0002-3116-6922
Ding, Bao-Jian
0000-0003-3322-6148
Wang hong-lei
Applicants
- Technical University of Denmark
[NORA names: DTU Technical University of Denmark; University; Denmark; Europe, EU; Nordic; OECD]
Abstract
A yeast cell capable of producing a desaturated fatty alcohol and optionally a desaturated fatty acyl acetate, wherein the yeast cell expresses:
i) at least one heterologous desaturase capable of introducing at least one double bond into a fatty acyl CoA having a carbon chain length of 14, and
ii) at least one heterologous fatty acyl CoA reductase (FAR) capable of converting at least a portion of the desaturated fatty acyl CoA to a desaturated fatty alcohol; and
iii) optionally, an acetyltransferase capable of converting at least a portion of the desaturated fatty alcohol to a desaturated fatty acyl acetate; wherein the desaturase has a higher specificity to tetradecanoyl-CoA than to hexadecanoyl-CoA and / or wherein the fatty acyl-CoA reductase has a higher specificity to desaturated tetradecanoyl-CoA than to desaturated hexadecanoyl-CoA.
Patent Family Records (21)
Production of desaturated fatty alcohols and desaturated fatty alcohol acetates in yeast
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, C. Holken Brink, M.I. Damm, (...more)
2024, CN-110291193-B
Production of desaturated fatty alcohols and desaturated fatty acyl acetates in yeast
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, DAM MARIE LNGER, (...more)
2023, US-20230135852-A1
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST.
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2023, MX-2022015233-A
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2023, HU-E060726-T2
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2023, HR-P20221360-T1
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ALCOHOL ACETATES IN YEAST
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2023, EP-4159850-A1
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2022, ZA-201903482-B
Production of desaturated fatty alcohols and desaturated fatty alcohol acetates in yeast
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2022, US-11434506-B2
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2022, RS-63726-B1
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2022, PL-3555269-T3
Production of unsaturated fatty alcohols and unsaturated fatty acyl acetates in yeast
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2022, ES-2930358-T3
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2022, EP-3555269-B1
Production of unsaturated fatty alcohols and unsaturated fatty acyl acetates in yeast
Technical University of Denmark, UNIV DANMARKS TEKNISKE Holkenbrink, Carina, Dam, Marie Inger, Löfstedt, Christer, (...more)
2022, DK-3555269-T3
YEAST CELL, METHOD FOR PRODUCTION OF A DESATURATED FATTY ALCOHOL AND OPTIONALLY A DESATURATED FATTY ALCOHOL ACETATE, AND KIT OF PARTS
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2022, BR-112019012276-B1
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2020, US-20200102582-A1
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST.
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2019, MX-2019007048-A
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2019, EP-3555269-A1
PRODUCTION OF SATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACID ACYL ACETATES IN Yeast
Danmarks Tekniskie Universitet, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2019, DE-17825466-T1
Desaturation fatty alcohol and desaturation fatty acyl group acetic acid esters are generated in yeast
TECHNICAL UNIVERSITY OF DENMAR, Technical University of Denmark Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2019, CN-110291193-A
yeast cell, method for producing a desaturated fatty acid and optionally a desaturated fatty acyl acetate, nucleic acid construction, kit of parts, desaturated fatty alcohol or a desaturated fatty acy...
Technical University of Denmark, UNIV DANMARKS TEKNISKE Ding, Bao-Jian, Holkenbrink, Carina, Löfstedt, Christer, (...more)
2019, BR-112019012276-A2
PRODUCTION OF DESATURATED FATTY ALCOHOLS AND DESATURATED FATTY ACYL ACETATES IN YEAST
Technical University of Denmark, UNIV DANMARKS TEKNISKE Borodina, Irina, Holkenbrink, Carina, Dam, Marie Inger, (...more)
2018, WO-2018109167-A1