Patent-family-89473439

The present invention relates in one aspect to a gastroenteroanastomosis device for use in a minimally invasive procedure for forming a passage across apposed tissue walls from the stomach to a target portion of the small intestines in a patient. The device is transformable from a collapsed state configured for minimally invasive delivery of the device to a gastro-enteric deployment site in the apposed tissue walls to a deployed state configured for deployment at the gastro-enteric deployment site. The device comprises, when the device is seen in the deployed state: a first part adapted for enteric placement; a second part adapted for gastric placement; and a centrally arranged mechanical connection forcing the first and second parts towards each other in an axial direction. The first part comprises a first engagement region; the second part comprises a second engagement region facing towards the first engagement region; and the first and second engagement regions are adapted to engage the apposed tissue walls there between to apply an ischemic pressure. The first part further comprises a first peripheral region enclosing the first engagement region in a peripherally outward direction; the second part further comprises a second peripheral region enclosing the second engagement region in a peripherally outward direction and facing towards the first peripheral portion; wherein the first and second peripheral regions are adapted to contact the apposed tissue walls there between to apply a non-ischemic pressure. The first and second peripheral regions gradually diverge from each other, whereby the first and second peripheral regions cooperate to gradually reduce, in an outward going direction from the engagement region to a periphery of the device, a pressure applied to the apposed tissue walls from ischemic pressure at the engagement region to no pressure at the periphery, passing through a non-ischemic pressure regime.