Antibodies capable of binding CD27, variants thereof and uses thereof

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Abstract

The present invention relates to antibodies capable of binding human CD27 and variants thereof comprising a modified Fc region comprising one or more mutations that enhance Fc-Fc interactions of the antibodies. The invention also provides pharmaceutical compositions comprising said antibodies and the use of said antibodies for therapeutic and diagnostic procedures, in particular in cancer treatment.

Patent Family Records (1)

Antibodies capable of binding CD27, variants thereof and uses thereof

Jian Mabao A. Yoan, U. Shaxin, F. Ji se Ke, (...more) MUCK ALEXANDER, K. Schedel, F. Bai Sikensi, R. de Rong, J. Schulman, E. C.W. Brege, I. al tastas, P. L. Degoye, D. Satijin, P. Boros (fewer)

2024, CN-118055950-A

Data Provider: Digital Science