VACCINES COMPRISING VIRUS-LIKE PARTICLES DISPLAYING SARS-COV-2 ANTIGENS AND METHODS OF USE
Applicants:
- Bavarian Nordic (Denmark) [NORA names: Bavarian Nordic; Private Research; Denmark; Europe, EU; Nordic; OECD]
- BAVARIAN NORDIC AS [NORA names: Bavarian Nordic; Private Research]
- ADAPTVAC APS [NORA names: Other Companies; Private Research]
Abstract
The invention provides vaccines comprising virus-like particles displaying at least one SARS-CoV-2 antigen. Virus-like particles (VLPs) comprising AP205 protein display antigens such as the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein using a connection comprising a peptide tag and binding partner. The invention also relates to methods of treatment using the VLPs of the invention and use of the VLPs to treat and/or prevent infection with the SARS-CoV-2 virus and variants thereof. The invention further relates to medical uses of the VLPs in the prevention and/or amelioration of COVID-19 symptoms.
Patent Family Records (1)
VACCINES COMPRISING VIRUS-LIKE PARTICLES DISPLAYING SARS-COV-2 ANTIGENS AND METHODS OF USE
ADAPTVAC APS, BAVARIAN NORDIC AS, Bavarian Nordic (Denmark) VOLKMANN ARIANE, BERTELSEN ADAM FREDERIK SANDER
2022, WO-2022229817-A1