MODIFIED PEPTIDE-OLIGONUCLEOTIDE CONJUGATE

Patent Number: WO-2023093960-A1

Publication Year: 2023

Application Year: 2022

Priority Year: 2021

Jurisdictions: WO

Status: N/A

Inventors:

Wengel, Jesper Thagaard 0000-0001-9835-1009 PEREIRA SARA RAQUEL DO SOUTO Santos, Rita Sobral 0000-0002-7174-271X Moreira, Luís Azevedo, Nuno Filipe 0000-0001-5864-3250 Guimarães, Nuno Miguel Rocha 0000-0002-7623-3877

Applicants:

  1. University of Southern Denmark
  2. [NORA names: SDU University of Southern Denmark; University; Denmark; Europe, EU; Nordic; OECD]
  3. University of Porto
  4. [NORA names: Portugal; Europe, EU; OECD]

Abstract

The present invention relates to a modified peptide-oligonucleotide conjugates (POC) composed of a cell-penetrating peptide (CPP) conjugated to an antisense oligonucleotide. The POC is able to regulate gene expression in the target cells and can thus be used in treatment of different disease such as bacterial infections and cancer.

Patent Family Records (1)

MODIFIED PEPTIDE-OLIGONUCLEOTIDE CONJUGATE

UNIV OF PORTO, UNIV SYDDANSK, University of Porto, University of Southern Denmark Wengel, Jesper Thagaard, PEREIRA SARA RAQUEL DO SOUTO, Santos, Rita Sobral, (...more)

2023, WO-2023093960-A1

Data Provider: Digital Science