Patents - Global Data - Dimensions
TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF
Inventors:
Appel, Eric Andrew
0000-0002-2301-7126
Appel, Eric Andrew
0000-0002-2301-7126
Appel, Eric Andrew
0000-0002-2301-7126
Gale, Emily C
0000-0002-6536-3027
Gale, Emily C
0000-0002-6536-3027
Gale, Emily C
0000-0002-6536-3027
Smith, Anton Allen Abbotsford
0000-0001-6728-5299
Smith, Anton Allen Abbotsford
0000-0001-6728-5299
Smith, Anton Allen Abbotsford
0000-0001-6728-5299
Roth, Gillie Agmon
0000-0002-3451-3694
Roth, Gillie Agmon
0000-0002-3451-3694
Roth, Gillie Agmon
0000-0002-3451-3694
Applicants:
- Aarhus University [NORA names: AU Aarhus University; University; Denmark; Europe, EU; Nordic; OECD]
- Stanford University [NORA names: United States; America, North; OECD]
Abstract
The present disclosure provides nanoparticles comprising a polymer and a plurality of TLR agonist moieties conjugated to the polymer and present on the surface of the nanoparticles. Methods of producing the nanoparticles, hydrogels comprising the nanoparticles, and vaccines comprising the nanoparticles and/or hydrogels are also provided. Methods for inducing an antigen-specific humoral immune response or enhancing cancer immunotherapy in a subject are also provided.
Patent Family Records (3)
TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF
Aarhus Universitet, Aarhus University, Leland Stanford Junior University, Stanford University Appel, Eric Andrew, Gale, Emily C, Smith, Anton Allen Abbotsford, (...more)
2024, EP-4149550-A4
TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF
Leland Stanford Junior University, Stanford University Appel, Eric Andrew, Gale, Emily C, Smith, Anton Allen Abbotsford, (...more)
2023, US-20230173059-A1
TOLL-LIKE RECEPTOR (TLR) AGONIST NANOPARTICLES AND USES THEREOF
Aarhus Universitet, Aarhus University, Leland Stanford Junior University, Stanford University Appel, Eric Andrew, Gale, Emily C, Smith, Anton Allen Abbotsford, (...more)
2023, EP-4149550-A1
