Patents - Global Data - Dimensions
Generation of endocrine progenitor cells from human pluripotent stem cells using small molecules
Applicants:
- Novo Nordisk (Denmark) [NORA names: Novo Nordisk; Private Research; Denmark; Europe, EU; Nordic; OECD]
- Takara (Sweden) [NORA names: Sweden; Europe, EU; Nordic; OECD]
Abstract
A method for obtaining NGN3 / NKX2.2 positive double endocrine progenitor cells, wherein a population of cells comprising pancreatic endoderm cells is simultaneously exposed in a basal medium to: a) a TGF-ß type I receptor inhibitor, b) a BMP antagonist, wherein the BMP antagonist is nogin, c) an adenylate cyclase activator, and d) nicotinamide.
Patent Family Records (1)
Generation of endocrine progenitor cells from human pluripotent stem cells using small molecules
Novo Nordisk (Denmark), Novo Nordisk AS, Takara (Sweden), Takara Bio Europe AB DØHN ULRIK, CHRISTOPHERSEN NICOLAJ STRØYER, EKBERG JENNY
2020, ES-2746232-T3
